Most general uses of compass point directions will be lower case.
Take the highway north from the east end of town, and you’ll reach the hotel in 10 minutes.
Where a compass point is part of a place name, including conceptual ones, use title case.

Most general uses of compass point directions will be lower case.
Take the highway north from the east end of town, and you’ll reach the hotel in 10 minutes.
Where a compass point is part of a place name, including conceptual ones, use title case.
Although spelling out compass points in full is best for body text, in some cases a shortened form is appropriate.
For example, if you’re writing in a specialist or scientific context, such as to an audience of meteorologists, the shortened forms may be fine. More commonly, you may want to use shortened forms where space is limited, such as in tables and graphs.
In either case, capitalise all letters that represent each word in a compass point. Don’t add hyphens in the short form, even if they would appear in the spelled out version.